Stimulated Raman Activated Cell Sorting

Stimulated Raman Activated Cell Sorting

MicroscopyCell sortingImage processingMultimodal imaging

Cell sorting is essential for many biological applications. Our new approach uses stimulated Raman spectroscopy for label-free cell sorting.

Our study has been reported by FIO+LS:Scientists invent new way to sort cells by type using light and Raman spectroscopy improves single-cell sorting

Our paper can be found at Science Advances 2024. adn6373

Overview of the Stimulated Raman Activated Cell Sorting system.

Target identification based on Raman profile with spatial constrains.

Detailed cell sorting process.

Downstream analysis of the sorted cells.

This technique allows for high-throughput analysis and sorting of cells based on their intrinsic chemical properties without the need for labels or markers.

The system can detect metabolic differences in cellular composition, enabling new applications in cancer research, stem cell biology, and pharmaceutical development.